A fabrication platform for electrically mediated optically active biofunctionalized sites in BioMEMS.
basic_science · Level V
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Abstract
We report a new approach for microfluidic optical bioanalysis that is based on the electrically driven assembly of bio-components on a transparent sidewall and the optical detection of the assembled components using planar waveguides. This allows localized electrical signals for bio-assembly and optical signals for bio-detection that can easily be applied in MEMS systems. We demonstrate a BioMEMS design incorporating this scheme and its output signal when using fluorescent detection.
Medical subject headings
- Biomimetics
- Biosensing Techniques
- Microfluidics
- Microscopy, Fluorescence