SECISDesign: a server to design SECIS-elements within the coding sequence.
other · Level V
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Abstract
SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli. The server is available at http://www.bio.inf.uni-jena.de/Software/SECISDesign/index.html.
Medical subject headings
- Escherichia coli
- Protein Engineering
- Proteins
- Sequence Analysis, Protein
- Sequence Analysis, RNA
- Software