Human T-cell leukemia virus type I at age 25: a progress report.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 15930259.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
It has been 25 years since the discovery of human T-cell leukemia virus type I (HTLV-I) and its role in adult T-cell leukemia. Here, in brief, we review the current state of our understanding of HTLV-I epidemiology, viral biology, pathogenesis, and treatment. We discuss how HTLV-I may transform cells through destabilization of cellular genomic integrity and induction of cellular tolerance for chromosomal errors.
Medical subject headings
- HTLV-I Infections
- Human T-lymphotropic virus 1
- Leukemia-Lymphoma, Adult T-Cell