A review of Streptococcus pneumoniae infection treatment failures associated with fluoroquinolone resistance.
review · Level V
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Abstract
We reviewed all of the published reports of cases of fluoroquinolone treatment failures for respiratory tract infection due to fluoroquinolone-resistant Streptococcus pneumoniae. There were 20 ciprofloxacin and levofloxacin treatment failures reported. Physicians should be aware, when treating pneumococcal respiratory tract infections in older patients with a fluoroquinolone, that clinical failures might occur, especially for patients with comorbid illnesses and a history of recent fluoroquinolone use.
Medical subject headings
- Anti-Bacterial Agents
- Drug Resistance, Bacterial
- Fluoroquinolones
- Pneumococcal Infections
- Respiratory Tract Infections
- Streptococcus pneumoniae