Reinforcing the mucus: a new therapeutic approach for ulcerative colitis?
review · Level V
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- Record sourced from PubMed, PMID 15951531.
- Also identified by PMC identifier 1774597.
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Abstract
Luminal delivery of phosphatidyl rich phospholipids appears to reduce mucosal inflammatory activity in a high proportion of patients with chronically active ulcerative colitis. The simplicity and apparent safety of this therapeutic approach offers new insights into the importance of the mucus barrier in the pathogenesis and treatment of ulcerative colitis.
Medical subject headings
- Colitis, Ulcerative
- Mucus
- Phospholipids