Getting downstream without a Raft.
review · Level V
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- Record sourced from PubMed, PMID 15960968.
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Abstract
The role of plasma-membrane microdomains in the organization of signaling proteins has been a controversial topic in T cell signaling. In this issue of Cell, use of single-molecule fluorescence suggests that protein-protein interactions, not detergent insolubility, regulate the assembly of signaling complexes in the plasma membrane.
Medical subject headings
- Biomarkers
- Green Fluorescent Proteins
- Membrane Microdomains