Restless legs syndrome and low brain iron levels in patients with haemochromatosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 15965214.
- Also identified by PMC identifier 1739708.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Regional brain iron levels of two patients with haemochromatosis and severe restless legs syndrome (RLS) were assessed using R2' magnetic resonance imaging (MRI) sequences in both patients and in nine healthy controls. R2' relaxation rates in the patients were decreased in the substantia nigra, red nucleus, and pallidum when compared with the controls. These results indicate that local brain iron deficiency may occur in patients with haemochromatosis and suggest a role for brain iron metabolism in the pathophysiology of RLS.
Medical subject headings
- Brain
- Brain Diseases
- Hemochromatosis
- Iron
- Magnetic Resonance Imaging
- Restless Legs Syndrome