Mathematical models of cell cycle regulation.
review · Level V
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- Record sourced from PubMed, PMID 15975225.
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Abstract
The cell division cycle is a fundamental process of cell biology and a detailed understanding of its function, regulation and other underlying mechanisms is critical to many applications in biotechnology and medicine. Since a comprehensive analysis of the molecular mechanisms involved is too complex to be performed intuitively, mathematical and computational modelling techniques are essential. This paper is a review and analysis of recent approaches attempting to model cell cycle regulation by means of protein-protein interaction networks.
Medical subject headings
- Cell Cycle
- Cell Cycle Proteins
- Gene Expression Regulation
- Models, Biological
- Signal Transduction