Stem cell grand SLAM.
review · Level V
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- Record sourced from PubMed, PMID 15989946.
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Abstract
Stem cells in both embryonic and adult tissues are defined by their unique ability to balance self-renewal and differentiation such that mature cells necessary for tissue function can be generated and replaced without depletion of the stem cell pool. In this issue of Cell, report a major step forward for studying the mechanisms and regulation of such stem cell fate decisions in the blood-forming (hematopoietic) system by providing a simple and broadly applicable method to isolate these cells and to visualize them in their normal environment.
Medical subject headings
- Cell Differentiation
- Cell Lineage
- Glycoproteins
- Hematopoiesis
- Hematopoietic Stem Cells
- Immunoglobulins