TICO: a tool for improving predictions of prokaryotic translation initiation sites.
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Abstract
We provide the tool 'TICO' (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations. Our tool can be freely accessed through a web interface at http://tico.gobics.de/ maike@gobics.de
Medical subject headings
- Algorithms
- Codon, Initiator
- Genome, Bacterial
- Protein Biosynthesis
- Sequence Analysis, DNA
- Software