Efficacy of rituximab in refractory polymyositis.

Lambotte, Olivier; Kotb, Rami; Maigne, Gwenola; Blanc, François-Xavier; Goujard, Cécile; Delfraissy, Jean François · J Rheumatol · 2005

case_report · Level V

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Abstract

We describe the effectiveness of rituximab, an anti-B lymphocyte monoclonal antibody, in a case of refractory polymyositis with interstitial pulmonary disease and anti-Jo-1 autoantibody (antisynthetase syndrome). Rituximab was well tolerated, and its efficacy in inflammatory myositis should be evaluated.

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