Left ventricular assist device as destination therapy in doxorubicin-induced cardiomyopathy.

Simsir, Sinan A; Lin, Shu S; Blue, Laura J; Gockerman, John P; Russell, Stuart D; Milano, Carmelo A · Ann Thorac Surg · 2005

case_report · Level V

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Abstract

Doxorubicin-induced cardiomyopathy is not uncommon and may progress to end-stage heart failure. Treatment of this condition with heart transplantation, however, requires that the primary malignancy be deemed "cured." We present the case of a 55- year-old woman who had doxorubicin-induced cardiomyopathy and non-Hodgkin's lymphoma. The active status of her lymphoma precluded heart transplantation. She had end-stage heart failure and underwent the insertion of a left ventricular assist device as a destination therapy.

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