The smoking-thrombolysis paradox and acute ischemic stroke.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 16043802.
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Abstract
Smokers with acute myocardial infarction have better outcomes after thrombolysis than nonsmokers. The authors evaluated the independent effect of smoking on short-term outcome following IV thrombolysis for acute ischemic stroke. After adjusting for covariates, recent smokers who received thrombolysis had a significantly greater drop in 24-hour median stroke severity scores from baseline than nonsmokers who received thrombolysis and lower mortality over 1 year.
Medical subject headings
- Brain Ischemia
- Cerebrovascular Disorders
- Fibrinolytic Agents
- Smoking
- Stroke