Initial diagnoses given to persons with the fragile X associated tremor/ataxia syndrome (FXTAS).

Hall, D A; Berry-Kravis, E; Jacquemont, S; Rice, C D; Cogswell, J; Zhang, L; Hagerman, R J; Hagerman, P J et al. · Neurology · 2005

case_series · Level IV

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Abstract

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a newly described disorder that occurs in premutation carriers of the fragile X mental retardation 1 (FMR1) gene. Fifty-six patients with FXTAS were given 98 prior diagnoses: most were in the categories of parkinsonism, tremor, ataxia, dementia, or stroke. Data from this study and others were used to develop guidelines for FMR1 diagnostic testing for FXTAS.

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