The prognosis of hearing impairment complicating HIV-negative cryptococcal meningitis.

Wang, H-C; Chang, W-N; Lui, C-C; Peng, J-P; Huang, C-R; Chang, H-W; Liliang, P-C; Lu, C-H · Neurology · 2005

case_series · Level IV

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Abstract

Eight patients who had sensorineural hearing loss (SNHL) associated with cryptococcal meningitis were studied. After a minimum 3-year follow-up, one had died. Among the seven survivors, three had improved, two stabilized, and two progressed. Predictive factors included visual disturbance, meningeal enhancements on MRI, and a CSF cryptococcal antigen titer of >1:1,024. SNHL accounted for 30.8% (8/26) of cryptococcal meningitis patients in our study.

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