CAR: three new models for a problem child.
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Abstract
By comparison with its older and better-behaved cousins in the nuclear receptor superfamily, CAR (NR1I3) has always been an oddball. Three new crystal structures recently described in Molecular Cell reveal the molecular basis for some of its bad habits (Xu et al., 2004; Suino et al., 2004; Shan et al., 2004).
Medical subject headings
- Receptors, Cytoplasmic and Nuclear
- Transcription Factors