Cellular iron: ferroportin is the only way out.
review · Level V
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- Record sourced from PubMed, PMID 16054057.
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Abstract
Ferroportin is the sole cellular efflux channel for iron and is regulated by the iron regulatory hormone hepcidin, which binds ferroportin and induces its internalization and degradation. New studies of ferroportin knockout mice define a key role for this transporter in physiological iron balance.
Medical subject headings
- Cation Transport Proteins
- Iron