Energizer: PGC-1 alpha keeps the heart going.

Sano, Motoaki; Schneider, Michael D · Cell Metab · 2005

editorial · Level V

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Abstract

In the current issue of Cell Metabolism, Arany et al. (2005) demonstrate essential roles for PGC-1alpha in cardiac metabolism, proving several long-postulated functions while disproving others. These experiments conclusively reinforce the logic of rescuing PGC-1alpha as a novel therapeutic target in heart failure.

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