Holding the line on hepatic fat.
editorial · Level V
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Abstract
When chronically elevated, insulin increases hepatic lipogenesis and VLDL synthesis. However, the hormone reduces liver lipids when acutely elevated. Work in this issue of Cell Metabolism (Najjar at al., 2005) suggests a new mechanism for the inhibition of the rate-limiting enzyme in liver, fatty acid synthase.
Medical subject headings
- Antigens, CD
- Fatty Acid Synthases
- Insulin
- Lipid Metabolism
- Liver