When pouring water on the fire makes it burn brighter.

Fogelman, Alan M · Cell Metab · 2005

basic_science · Level V

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Abstract

Earlier work seems to suggest that overexpression of uncoupling protein 1 would be anti-inflammatory. However, new findings show that expression of uncoupling protein 1 in aortic smooth muscle cells of mice increases reactive oxygen species, activates the renin-angiotensin system, elevates blood pressure, and worsens atherosclerosis.

Medical subject headings