A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster.
rct · Level II
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- Record sourced from PubMed, PMID 16087911.
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Abstract
This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.
Medical subject headings
- Amines
- Cyclohexanecarboxylic Acids
- Herpes Zoster
- Hyperalgesia
- Pain Threshold
- gamma-Aminobutyric Acid