Reduced amplitude of the sural nerve sensory action potential in PARK2 patients.
cross_sectional · Level IV
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Abstract
The authors performed nerve conduction studies in nine PARK2 and eight idiopathic Parkinson disease patients and found a significant reduction of sural sensory nerve action potential (SNAP) amplitude in eight PARK2 patients who mostly remained asymptomatic. These data suggest that sensory axonal neuropathy may be a common clinical feature of PARK2 and a reduced amplitude of sural SNAP could be a diagnostic indicator of PARK2.
Medical subject headings
- Parkinsonian Disorders
- Peripheral Nervous System Diseases
- Sensation Disorders
- Sural Nerve