Frontotemporal dementia with ubiquitinated neuronal inclusions and visuospatial impairment.

Meiner, Z; Newman, J P; Rosenman, H; Soffer, D; Steiner, I · Neurology · 2005

case_report · Level V

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Abstract

Dementia with ubiquitinated neuronal inclusions has been described only with frontotemporal dementia (FTD). The authors report a patient with progressive FTD accompanied by prominent impairments in visuospatial cognitive functions. Pathology was characterized by ubiquitin-positive intranuclear and cytoplasmic neuronal inclusions. Cortical pathology was widespread and posteriorly accentuated but spared the hippocampal dentate gyrus.

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