Development of multifunctional polymer-mineral composite materials for bone tissue engineering.
basic_science · Level V
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- Record sourced from PubMed, PMID 16088900.
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Abstract
The main goal of this article is the development of a novel approach to construct multifunctional composite scaffolds for bone tissue engineering. For this purpose, different kinds of mineral macroporous supports, water-soluble aldehyde-containing copolymers of N-vinylpyrrolidone, as well as different nonspecific and biospecific ligands governing cell adhesion and growth have been used. The composite materials were tested initially for cytotoxicity in cell culture experiments using a model cell line.
Medical subject headings
- Bone Substitutes
- Bone and Bones
- Coated Materials, Biocompatible
- Minerals
- Polymers
- Tissue Engineering