Splicing misplaced.

Meshorer, Eran; Misteli, Tom · Cell · 2005

editorial · Level V

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Abstract

Newly synthesized transcripts are usually spliced during transcription or immediately thereafter. So pre-mRNA splicing has been presumed to occur exclusively in the cell nucleus. In this issue of Cell, Denis et al. (2005) now report the presence of functional spliceosomes and signal-dependent pre-mRNA splicing in the cytoplasm of platelets.

Medical subject headings