A SIRTain role in pancreatic beta cell function.
other · Level V
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Abstract
Genes formerly thought to be involved solely in the regulation of life span have increasingly become implicated in the regulation of metabolic processes. Moynihan et al.(2005[this issue of Cell Metabolism]) now demonstrate that increasing levels of Sirt1 in the pancreatic beta cells of mice result in a more efficient glucose handling due to enhanced glucose-stimulated insulin secretion.
Medical subject headings
- Glucose
- Islets of Langerhans
- Sirtuins