High prevalence of viral genomes and inflammation in peripartum cardiomyopathy.

Bültmann, Burkhard D; Klingel, Karin; Näbauer, Michael; Wallwiener, Diethelm; Kandolf, Reinhard · Am J Obstet Gynecol · 2005

case_series · Level IV

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Abstract

Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy.

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