White matter lesion severity in male and female patients with Fabry disease.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 16116124.
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Abstract
In male patients with Fabry disease (FD), significant age-related cerebral white matter lesions (WMLs) can be found. Although characteristic symptoms including cerebrovascular events are highly prevalent also in females with FD, cerebral structural changes have not been investigated in female FD patients yet. The authors quantified the WML load of 13 male and 14 age-matched female patients with FD and could demonstrate a comparably high frequency and severity of WMLs in both groups.
Medical subject headings
- Cerebral Arteries
- Cerebral Infarction
- Cerebrovascular Disorders
- Fabry Disease
- Nerve Fibers, Myelinated