The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.
review · Level V
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Abstract
Hepatoblastoma is associated with familial adenomatous polyposis (FAP). In a series of 93 patients with hepatoblastoma,8 (8.6%) reported family histories suggestive of FAP. These and a review of reported FAP kindreds with hepatoblastoma may provide information helpful in counseling families with FAP.
Medical subject headings
- Adenomatous Polyposis Coli
- Genes, APC
- Hepatoblastoma
- Liver Neoplasms