Mid-dermal elastolysis with inflammation.

Brod, B A; Rabkin, M; Rhodes, A R; Jegasothy, B V · J Am Acad Dermatol · 1992

case_report · Level V

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Abstract

A 71-year-old white woman had finely wrinkled, erythematous patches of skin that met the clinical and histologic criteria for mid-dermal elastolysis. In addition to the loss of mid-dermal elastin described in previous cases, histopathologic examination revealed a superficial and deep perivascular inflammatory infiltrate of lymphocytes and plasma cells and interstitial collections of multinucleated giant cells containing phagocytized elastin. These results support a previously postulated inflammatory pathogenesis for mid-dermal elastolysis.

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