HIV controllers: a homogeneous group of HIV-1-infected patients with spontaneous control of viral replication.

Lambotte, Olivier; Boufassa, Faroudy; Madec, Yoann; Nguyen, Ahn; Goujard, Cécile; Meyer, Laurence; Rouzioux, Christine; Venet, Alain et al. · Clin Infect Dis · 2005

case_series · Level IV

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Abstract

We identified a total 15 patients who have maintained undetectable plasma HIV RNA loads without antiretroviral treatment for >10 years from cohorts of 1300 and 1551 patients infected with human immunodeficiency virus (HIV). These 15 patients, whom we have referred to as "HIV controllers," are characterized by a low HIV DNA load in peripheral blood mononuclear cells and by a strong HIV-specific immune response.

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