Rapid improvement of calcinosis in juvenile dermatomyositis with alendronate therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 16142885.
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Abstract
A 6-year-old boy with improving juvenile dermatomyositis (JDM) developed severe and debilitating calcinosis, unresponsive to diltiazem and probenecid. Alendronate produced dramatic improvement within 1 month and by 12 months calcinosis had virtually resolved. The response was followed by bone mineral content measurements.
Medical subject headings
- Alendronate
- Calcinosis
- Dermatomyositis