Helicobacter pylori eradication: equivalence trials and the optimal duration of therapy.

Vakil, Nimish; Connor, Jason · Am J Gastroenterol · 2005

review · Level V

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Abstract

Equivalence trials are gaining popularity and seek to compare the efficacy of two different types of treatment. The design of these trials requires careful consideration of clinical, statistical, and regulatory concerns. We discuss the importance and key factors relevant to equivalence trials.

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