Autonomic function after botulinum toxin type A or B: a double-blind, randomized trial.
rct · Level II
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Abstract
To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.
Medical subject headings
- Autonomic Nervous System
- Autonomic Nervous System Diseases
- Botulinum Toxins
- Botulinum Toxins, Type A
- Cholinergic Fibers
- Torticollis