Contrast-enhanced dark lumen PET/CT and MR colonography in a rodent polyp model: initial results with histopathologic correlation.

Kuehle, Christiane A; Veit, Patrick; Antoch, Gerald; Grabellus, Florian; Robert, Philippe; Beyer, Thomas; Herborn, Christoph U · AJR Am J Roentgenol · 2005

basic_science · Level V

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Abstract

The objective of this study was to assess the feasibility of PET/CT for the detection of colorectal masses in a rodent polyp model in an intraindividual comparison with dark-lumen MR colonography. Detection of small tumors with PET/CT and MR colonography is possible in a rodent model. The technique thus warrants further evaluation in animal studies as well as in patients with suspected colorectal disease.

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