Asynchronous burst-suppression in a child with callosal Ki-1 anaplastic large cell lymphoma.

Hukin, J; Davey, A; Wong, P; Hendson, G; Aquino-Parsons, C; Wu, J; Sargent, M · Neurology · 2005

case_report · Level V

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Abstract

A 13-year-old girl with Ki-1 anaplastic large cell lymphoma (Ki-1ALCL) bulky deposits in the brain developed raised intracranial pressure and coma associated with asynchronous burst-suppression following standard dose cranial irradiation. Supportive care, steroids, and chemotherapy resulted in clinical improvement. Burst-suppression coma may be reversible when secondary to tumor, decrease in steroids, or radiation effects; the asynchrony localizes the lesion to cortical interconnections such as the corpus callosum.

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