Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation.

Marcel, M; Leys, D; Mounier-Vehier, F; Bertheloot, D; Lartigau, E; Pruvo, J P; Al-Koussa, M; Chevalier, D et al. · Neurology · 2005

prospective_cohort · Level II

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Abstract

The authors followed up 41 consecutive patients (21 symptomatic) with internal carotid artery stenosis > or =70% and previous neck irradiation. After 28 months, 15 patients (36.6%) had died, five (12.2%) had had an ischemic stroke, and 15 (36.6%) had a new malignancy. Having a new malignancy was the only independent predictor of death. The major risk for patients with ICA stenosis > or =70% and previous neck irradiation is malignancy, not stroke.

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