HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients.
basic_science · Level V
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Abstract
We have developed a simulation tool HapSim for the generation of haplotype data. The simulated haplotypes are such that their allele frequencies and linkage disequilibrium coefficients match exactly those estimated in a real sample. The program is available as an R package and can be downloaded from http://cran.r-project.org/.
Medical subject headings
- Computational Biology
- Linkage Disequilibrium