Radiation-induced spinal cord cavernous malformation. Case report.

Yoshino, Masanori; Morita, Akio; Shibahara, Junji; Kirino, Takaaki · J Neurosurg · 2005

case_report · Level V

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Abstract

The authors report a case of a 16-year-old girl who presented with progressive gait difficulty 8 years after undergoing spinal radiation therapy for spinal astrocytoma. Magnetic resonance imaging revealed intramedullary multicentric cavity formation in the T4-10 area. Extensive subtotal resection was performed and a pathological examination of the excised tissue demonstrated cavernous malformation with radiation-induced degeneration in the surrounding vessels. This is believed to be the third case of de novo formation of an intramedullary cavernous malformation following spinal radiation therapy.

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