Hereditary microphthalmia with colobomatous cyst.

Porges, Y; Gershoni-Baruch, R; Leibu, R; Goldscher, D; Zonis, S; Shapira, I; Miller, B · Am J Ophthalmol · 1992

case_report · Level V

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Abstract

We examined five members of a highly inbred kinship who had isolated microphthalmia associated with colobomatous cysts and various other ocular lesions. They were all offspring of consanguineous (first cousins) and unaffected parents. Microphthalmia in this kindred was transmitted as an autosomal recessive trait. Ultrasonography was effective for prenatal diagnosis in two pregnancies at risk.

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