Organogenesis of the endocrine pancreas.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 16221174.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Organogenesis of the endocrine pancreas. Embryonic pancreatic primordia transplanted into diabetic animal hosts undergo selective endocrine differentiation in situ and normalize glucose tolerance. Pancreatic primordia can be transplanted across isogeneic, allogeneic, and both concordant (rat to mouse) and highly disparate (pig to rodent) xenogeneic barriers. This review explores the therapeutic potential for pancreatic organogenesis posttransplantation of embryonic primordia.
Medical subject headings
- Diabetes Mellitus, Type 1
- Fetal Tissue Transplantation
- Islets of Langerhans
- Pancreas Transplantation
- Transplantation, Heterologous