Cutaneous IgA-associated vasculitis induced by alcohol.
case_report · Level V
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- Record sourced from PubMed, PMID 16225621.
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Abstract
A patient with elevated levels of serum IgA developed purpuric lesions histologically resembling Henoch-Schönlein purpura brought on by consuming alcohol. Alcohol challenge with 5 units of alcohol reproduced the lesions, with a rapid rise of circulating CD4+ and CD8+ T cells followed by a fall of serum IgA and C3 concentration. The skin lesions and serum abnormalities resolved spontaneously within 6 weeks of the alcohol challenge.
Medical subject headings
- Ethanol
- Immunoglobulin A
- Skin Diseases, Vascular
- Vasculitis