Diffuse leptomeningeal involvement by a ganglioglioma in a child. Case report.
case_report · Level V
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- Record sourced from PubMed, PMID 1625019.
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Abstract
Gangliogliomas are tumors composed of neuronal and glial elements that typically grow slowly by expansion only. This report describes a 20-month-old girl with a ganglioglioma that extensively involved the subarachnoid space; microscopic foci of tumor were found in the brain and spinal cord. Despite chemotherapy and radiation therapy, the child died 5 months after diagnosis. Molecular genetic analysis showed loss of chromosome 17p DNA sequences in the tumor tissue.
Medical subject headings
- Brain Neoplasms
- Neuroblastoma
- Subarachnoid Space