Familial pulmonary nodular lymphoid hyperplasia.

Franchi, L M; Chin, T W; Nussbaum, E; Riker, J; Robert, M; Talbert, W M · J Pediatr · 1992

case_report · Level V

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Abstract

We describe three persons in one family with diffuse lung infiltrates, digital clubbing, and chronic hypoxia. Elevated immunoglobulin levels and antinuclear antibodies were found in all patients; pathologic findings included hyperplastic lymphoid follicles infiltrating the epithelium of the small airways. These cases may represent a familial systemic autoimmune disorder seen primarily with pulmonary compromise.

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