Prophylactic antimicrobials for traveler's diarrhea: an early history.

Sack, R Bradley · Clin Infect Dis · 2005

review · Level V

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Abstract

The prevention of traveler's diarrhea by use of pharmacologic agents has been of great interest since the early 1960s. It was not until the discovery of enterotoxigenic Escherichia coli as the dominant causative organism of travelers' diarrhea, however, that rational antimicrobial therapy could be studied. Selected antimicrobials have proven to be highly efficacious, but, by consensus, are not widely used.

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