CSF amyloid beta42 and tau levels correlate with AIDS dementia complex.
cross_sectional · Level IV
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Abstract
There is concern that AIDS dementia complex (ADC) may be complicated by Alzheimer disease (AD). Because AD presence and risk are related to CSF beta-amyloid(1-42) (Abeta42), total tau (t-tau), and phosphorylated tau (p-tau), the authors examined these in ADC, AD, and controls. ADC had significantly decreased CSF Abeta42 and increased t-tau and p-tau concentrations similar to AD, suggesting that ADC may be associated with AD or an AD-like process.
Medical subject headings
- AIDS Dementia Complex
- Alzheimer Disease
- Amyloid beta-Peptides
- Peptide Fragments
- tau Proteins