Significance of phrenic nerve electrophysiological abnormalities in Guillain-Barré syndrome.
retrospective_cohort · Level III
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Abstract
The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain-Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and ventilated (n = 10) patients. In ventilated patients, motor loss severity, progression, and VC reduction were significantly greater, and bulbar dysfunction was more common. Predicting respiratory failure must rely on clinical features and VC.
Medical subject headings
- Diaphragm
- Guillain-Barre Syndrome
- Phrenic Nerve
- Respiratory Insufficiency