Massive allograft use in orthopedic oncology.

Abstract

Allograft transplantation is a functional reconstructive option for large-extremity osseous defects. Improvements in anatomic matching, infection prevention, allograft fixation, soft tissue reconstructions, and rehabilitation protocols have greatly influenced predictability and longevity of massive allografts. These demanding reconstructions require time, an experienced group of orthopedic surgeons working at an institution with access to a large volume of patients, and a reliable, modern bone bank to select the appropriate graft for each individual under safe conditions. This article discusses the current use of total condylar osteoarticular allografts, hemicondylar allografts, allograft arthrodesis, intercalary segmental allografts, hemicylindric intercalary allografts, and allograft-prosthesis composites.