Sinistral snails and gentlemen scientists.

Gurdon, J B · Cell · 2005

review · Level V

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Abstract

A single gene mutation can cause a complete left-to-right and right-to-left inversion of the body axis. This mutation exemplifies a large class of so-called maternal effect genes that regulate key events during early development. This principle was first established nearly one hundred years ago, principally by the work of amateur naturalists.

Medical subject headings