Can 1000 reviews be wrong? Actin, alpha-Catenin, and adherens junctions.

Gates, Julie; Peifer, Mark · Cell · 2005

review · Level V

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Abstract

Coupling between cell adhesion and the actin cytoskeleton is thought to require a stable link between the cadherin-catenin complex and actin that is mediated by alpha-catenin. In this issue of Cell, the Weis and Nelson groups call this static model into question, showing that alpha-catenin can directly regulate actin dynamics (Drees et al., 2005 and Yamada et al., 2005).

Medical subject headings